Bioactive triterpenoids from Indonesian medicinal plant <i>Syzygium aqueum</i>

Abstract A large common species, Syzygium aqueum , belonging to the genus possesses numerous bioactive phytochemical constituents. Moreover, different parts of this species have been used as folk medicine since centuries ago. In study, a exploration was carried out on plant’s stem bark. Isolation compounds through extraction step with some organic solvents, followed by separation and purification using chromatography techniques until two triterpenoids were isolated from nonpolar semipolar extracts. Structure elucidation done spectroscopic methods. These identified alphitolic acid arjunolic acid. Subsequently, these in anticancer tests against human cancer cells HeLa, T47D, A549 colorimetric assay. The result showed that both more inhibition growth HeLa T47D than cells, highest activity shown cell lines.